Hemoglobin Protein Dynamics

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Oxy to Deoxyhemoglobin transition: molecular motion

 

 

Histidine Structure

 

Central Cavity in deoxyhemoglobin which defines the DPG binding location

 

Note the reduced central cavity size in oxyhemoglobin with attendant prevention of DPG binding (http://www.udel.edu/chem/bahnson/Chem641/chime/Index.htm)

 

(2,3)-DPG

 

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