Peptic Ulcer Disease

Return to Section Table of Contents

Return to Site Table of Contents

Page Back

Chapter 21

Gastrointestinal Issues:  Gastrokinetic Agents,  Antacids as preoperative medication and Antiemetic Agents.

Pharmacological Management of Ulcer Disease

Table of Contents

Drug Treatment

Other GI Drugs 

Overview

"Benign chronic gastric ulcer: note sharp margins, flat relatively clean ulcer base and folds that radiate from the ulcer margin, location on the lesser curvature in the antrum at the fundopyloric junctional mucosa (precepitous proximal and sloping distal border not clearly seen)."

Courtesy of the University of Texas Health Science Center

http://medic.med.uth.tmc.edu/edprog/Path/Path-17a.htm

 

Gastric Physiology

"Regulation of Gastric secretion of HCL. The solid arrows indicate stimulation; the dashed arrow indicates inhibition. "

courtesy of Robert H. Parsons, Ph.D., Rensselaer Polytechnic Institute, used with permission

 Pathogenic Factors

Increased incidence associated with:
chronic renal failure renal transplantation systemic mastocytosis
alcoholic cirrhosis hyperparathyroidism chronic obstructive pulmonary disease (COPD)

Drug Treatment

"Parietal Cell-HCl secretion"

courtesy of Robert H. Parsons, Ph.D., Rensselaer Polytechnic Institute, used with permission

 

Friedman, L. S. and Peterson, W.L. Peptic Ulcer and Related Disorders In Harrison's Principles of Internal Medicine 14th edition, (Isselbacher, K.J., and Braunwald, E., Wilson, J.D., Martin, J.B., Fauci, A.S. and Kasper, D.L., eds) McGraw-Hill, Inc (Health Professions Division), 1998, pp. 1597-1616.

 

Return to Section Table of Contents

Return to Site Table of Contents

Page Back

 

Google