Sedative Hypnotics Drugs

Chapter 11:  Anxiolytics and Sedative-Hypnotics

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Learning Objectives: The student should know and be able to discuss:

[Hobbs, W.R, Rall, T.W., and Verdoorn, T.A., Hypnotics and Sedatives: Ethanol In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) TheMcGraw-Hill Companies, Inc.,1996, pp. 361-383.]

[Hibbs, W.R, Rall, T.W., and Verdoorn, T.A., Hypnotics and Sedatives: Ethanol In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) TheMcGraw-Hill Companies, Inc.,1996, pp. 364-367.]

[Hibbs, W.R, Rall, T.W., and Verdoorn, T.A., Hypnotics and Sedatives: Ethanol In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) TheMcGraw-Hill Companies, Inc.,1996, pp. 377.]

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Baldessarini, R. J., Drugs and the Treatment of Psychiatric Disorders, In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) TheMcGraw-Hill Companies, Inc.,1996, pp. 421-427]

[Hobbs, W.R, Rall, T.W., and Verdoorn, T.A., Hypnotics and Sedatives: Ethanol In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) TheMcGraw-Hill Companies, Inc.,1996, pp. 385-386

 

 

" Wernicke-Korsakoff encephalopathy. Note pigmentation of gray matter around third ventricle. Occurs with Vitamin B1 deficiency, most often in chronic alcoholics."--image from educational materials (pathology) University of Texas (Houston) (http://medic.med.uth.tmc.edu/edprog/path/path-10.htm)


"Mammillary Gross Wernicke's encephalopathy. Note bodies black mammillary body from acute congestion and hemorrhage indicating the acute form of Wernicke's" --image from educational materials (pathology) University of Texas (Houston) (http://medic.med.uth.tmc.edu/edprog/path/path-10.htm)

 

Hobbs, W.R, Rall, T.W., and Verdoorn, T.A., Hypnotics and Sedatives: Ethanol In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) TheMcGraw-Hill Companies, Inc.,1996, pp. 386-392.

[Hibbs, W.R, Rall, T.W., and Verdoorn, T.A., Hypnotics and Sedatives: Ethanol In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) TheMcGraw-Hill Companies, Inc.,1996, pp. 374-377.]

  1. [[Hobbs, W.R, Rall, T.W., and Verdoorn, T.A., Hypnotics and Sedatives: Ethanol In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) The McGraw-Hill Companies, Inc.,1996, pp. 372-373.;

  2. McNamara, J.O. Drugs Effective in the Therapy of the Epilepsies, In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) The McGraw-Hill Companies, Inc.,1996, pp. 479];

  3. Dopheide, J.A.. Sleep Disorders, In, Applied Therapeutics: The Clinical Use of Drugs, (Young, L.Y. and Koda-Kimble, M.A.,eds) Applied Therapeutics, Inc., 1995, p 74-5);

  4. [Harvery, R.A, Champe, P.C., Mycek, M.J., Gertner, S.B. and Perper, M.M., Anxiolytic and Hypnotic Drugs, In: Lippincott's Illustrated Reviews: Pharmacology, J.B. Lippincott Co, 1992, p 94]

  5. Eisendrath SJ and Lichtmacher JE "Psychiatric Disorders" in 2008 Current Medical Diagnosis and Treatment, (McPhee SJ, Papadakis MA and Tierney LM, eds) Lange 2008, McGraw Hill Medical, New York, 47th edition, 2008.

 

  1.  [Hibbs, W.R, Rall, T.W., and Verdoorn, T.A., Hypnotics and Sedatives; Ethanol In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) TheMcGraw-Hill Companies, Inc.,1996, pp. 364-367.]; 

  2. Baldessarini, R. J., Drugs and the Treatment of Psychiatric Disorders, In, Goodman and Gillman's The Pharmacologial Basis of Therapeutics,(Hardman, J.G, Limbird, L.E, Molinoff, P.B., Ruddon, R.W, and Gilman, A.G.,eds) TheMcGraw-Hill Companies, Inc.,1996, pp. 425]

 

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